The exact distribution of many applicable statistics could not be accessible in various statistical inference problems. To deal with such an issue in the large sample problem, an approach is to obtain the asymptotic distribution. In this article, we have expressed the asymptotic distribution of multivariate statistics class approximated by averages based on the Taylor expansion. Then, the asymptotic distribution of an empirical Mahalanobis depth-based statistic is obtained, and the statistic is applied to test the scale difference between two multivariate distributions. Simulation studies are carried out to explore the behavior of the asymptotic distribution of the test statistic. A real data example illustrating the use of the test is also presented.