There are several methods for inference about gene networks, but there are few cases in which the historical information have been considered. In this research we deal with Bayesian inference on gene network. We apply a Bayesian framework to use the available information. Assuming a proper prior distribution and taking the dependency of parameters into account, we seek a model to obtain promising results. We also deal with the hyper parameter estimation. Two methods are considered. The results will be compared by the use of a simulation based on Gibbs sampler. The strengths and weaknesses of each method are briefly mentioned.

One of the most frequently encountered longitudinal studies issues is data with losing the appointments or getting censoring. In such cases, all of the subjects do not have the same set of observation times. The missingness in the analysis of longitudinal discrete and continuous mixed data is also common, and missing may occur in one or both responses. Failure to pay attention to the cause of the missing (the mechanism of the missingness) leads to unbiased estimates and inferences. Therefore, in this paper, we investigate the mechanism of nonignorable missing in set-inflated continuous and zero-inflation power series, as well as the continuous and k-inflated ordinal mixed responses. A full likelihood-based approach is used to obtain the maximum likelihood estimates of the parameters of the models. In order to assess the performance of the models, some simulation studies are performed. Two applications of our models are illustrated for the American's Changing Lives  survey, and the Peabody Individual Achievement Test  data set.